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KMID : 0895820020120020003
Journal of Oriental Rehabilitation Medicine
2002 Volume.12 No. 2 p.3 ~ p.0
Effects of BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi) on the Recovery of Fatigue in the Swimming Loaded Rats
Kim Yeung-Khee

Lim Hyung-Ho
Abstract
Objects: This experiment was performed into investigate the effects of Bojungikgitang(Buzhongyiqitang) and BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi) on the recovery of fatigue in the swimming loaded rats by the lactic acid levels, creatine phosphokinase(CPK) activities, lactate dehydrogenase(LDH) activities and glucose levels, which are known as materials related to fatigue in blood.

Methods: On one hour before swimming exercise, the extracts of Bojungikgitang(Buzhongyiqitang) and BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi) were orally administered to the rats(Sprague-Dawley) which had been in the environment controlled rearing system for 2 weeks, and the control group were fed with equal amount of normal saline. And the lactic acid levels, creatine phosphokinase(CPK) activities, lactate dehydrogenase(LDH) activities and glucose levels in blood in rats were measured immediately and at thirty minutes after swimming exercise.

Results:
1. The lactic acid levels in BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi) group were decreased immediately after exercise and statistically showed the significant difference compared with the control group(P<0.05).
2. The creatine phosphokinase(CPK) activities in Bojungikgitang(Buzhongyiqitang) group were decreased immediately after exercise and statistically showed the significant difference compared with the control group(P<0.05), and in BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi) group were decreased immediately and at 30 minites after exercise and statistically showed the significant difference compared with the control group(P<0.05).
3. Lactate dehydrogenase(LDH) activities and glucose levels in Bojungikgitang(Buzhongyiqitang) group and BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi) group did not show the significant difference compared with the control group.

Conclusion: Based on the above results, we know that Bojungikgitang(Buzhongyiqitang) and BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi) have effects on the recovery of fatigue.
KEYWORD
Bojungikgitang(Buzhongyiqitang), BojungikgitanggaOgapi(Buzhongyiqitangjiawujiapi), Lactic acid, Creatine phosphokinase (CPK), Lactate dehydrogenase(LDH), Glucose
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